Research Associate, United Therapeutics

University of British Columbia


Job Class
School Non Bargaining

Job Title
Analysis Affiliate, United Therapeutics

Yachie Laboratory Faculty of Biomedical Engineering School of Drugs (Nozomu Yachie)

Posting Finish Date
October 18, 2023

Observe: Purposes shall be accepted till 11:59 PM on the day previous to the Posting Finish Date above.

Job Finish Date
Oct 15, 2024

At UBC, we consider that attracting and sustaining a various workforce is essential to the profitable pursuit of excellence in analysis, innovation, and studying for all college, employees and college students. Our dedication to employment fairness helps obtain inclusion and equity, brings wealthy variety to UBC as a office, and creates the mandatory situations for a rewarding profession. 

Place Abstract
The Faculty of Biomedical Engineering (SBME) on the College of British Columbia (UBC) in Vancouver, BC, Canada invitations purposes for Analysis Affiliate positions to work on a team-based challenge spanning pluripotent stem cells, lung differentiation, and genomics within the de Boer ( ), Shakiba ( ) , Yachie (, Zandstra ( ), and Lynn ( ) labs.

The challenge is in collaboration with United Therapeutics and seeks to allow the strong, large-scale manufacturing of lung cells from patient-specific induced pluripotent stem cells (iPSCs). The challenge includes using single-cell RNA-seq, DNA barcoding, reprogramming, and lung cell differentiation.

The Schools of Drugs and Utilized Science have partnered to create the SBME, a brand new flagship entity at UBC, and a prime strategic precedence for the College and each Schools. The SBME is a nucleus for training and coaching, analysis, and innovation in biomedical engineering, creating new data, new tutorial and coaching applications, and fostering translation and innovation. UBC SBME distinguishes itself by deep coaching in biology, and engineering science and design, enabling SBME researchers to handle essentially the most urgent biomedical challenges of the day. Our SBME college conduct analysis that advances our basic understanding of human biology, and yields applied sciences and therapies that advance our well being and wellbeing.

Organizational Standing

People will report back to a number of of Drs. Nika Shakiba, Dr. Carl de Boer, Dr. Nozomu Yachie, Dr. Francis Lynn, or Dr. Peter Zandstra, relying on the place, however will work collaboratively with groups throughout these labs regardless.


Profitable candidates can have the distinctive alternative to collaborate with the members of the laboratories concerned on this challenge, integrating cutting-edge stem cell, bioinformatics and artificial biology strategies.

The tasks of this place, to be decided by the Supervisor, are versatile and rely upon the abilities and analysis pursuits of the profitable applicant. Particular duties could embody:

  • Human pluripotent stem cell tradition together with upkeep, enlargement, and characterization

  • Derivation of induced pluripotent stem cells by means of reprogramming of PBMCs

  • Lung cell differentiation and tradition

  • Genetic engineering of mammalian cells

  • Subsequent era sequencing and bioinformatics evaluation

  • Machine studying/AI

  • Single-cell RNA-seq, perturb-seq, and/or different transcriptomic evaluation

  • Analyzing information and presenting the information in studies, publications, and shows at native and worldwide conferences

  • Serving to to reinforce our collaborative and interdisciplinary analysis surroundings.

  • Contributing to cutting-edge data within the scientific group

  • Getting ready grants and helping with grant purposes, publications and with fulfilling regulatory necessities (animal ethics, biosafety and so on.)

  • Designing and performing experiments, analyzing outcomes, and presenting findings

  • Coaching and mentoring lab personnel

  • Coordinating the upkeep of lab tools


  • Candidates with expertise in challenge administration shall be prioritized

  • Candidates should maintain a PhD or MD

  • Candidates ought to have a robust analysis background, as demonstrated by previous publications, accomplishments, and references

  • Candidates with robust background in both computational or experimental biology (or each) shall be thought-about

  • The profitable candidate shall be a passionate, self-driven, impartial thinker with wonderful organizational, oral and written communication, and interpersonal expertise, and a robust work ethic

  • Choice shall be given to experimental candidates who’ve expertise in any of the next areas: stem cell tradition, lentiviral supply, lung cell differentiation and tradition, iPSC derivation, transcriptomics, bioinformatics, single-cell RNA-seq

  • Choice shall be given to computational candidates who’ve expertise in any of the next subjects: bioinformatics, statistics, machine studying, deep studying, single cell omics, transcriptomics, and programming in R, Python, and Bash

Supervision acquired

The incumbent will obtain supervision instantly from a number of of Drs. Shakiba, de Boer, Yachie, Lynn, and Zandstra, relying on their actual function, however can have the chance to work intently with all laboratories concerned on this challenge.

Supervision given

The incumbent could also be required to oversee trainees concerned within the analysis program.

Begin date and stipend

The beginning date is as quickly as doable however versatile; funding has already been acquired. The place is full-time for one 12 months with the opportunity of extension topic to work efficiency. Wage shall be commensurate with {qualifications} and expertise.

The way to Apply

Candidates ought to present a CV, names and phone data of three references, and a canopy letter describing previous achievements and future analysis pursuits. Observe that there are a number of related positions obtainable and candidates ought to apply to any that curiosity them. Please submit your purposes instantly through Workday from this hyperlink.

For any inquiries relating to this place, please contact Dr. Nika Shakiba ([email protected] ), Dr. Nozomu Yachie (noz[email protected] ), and Dr. Carl de Boer ([email protected] ).

Fairness and variety are important to tutorial excellence. An open and numerous group fosters the inclusion of voices which have been underrepresented or discouraged. We encourage purposes from members of teams which have been marginalized on any grounds enumerated below the B.C. Human Rights Code, together with intercourse, sexual orientation, gender id or expression, racialization, incapacity, political perception, faith, marital or household standing, age, and/or standing as a First Nation, Metis, Inuit, or Indigenous particular person. 

All certified candidates are inspired to use; nonetheless, Canadians and everlasting residents of Canada shall be given precedence.

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