Master’s position in Experimental Medicine – Biomarker Research in…

The University of British Columbia (UBC)

Cystic fibrosis (CF) is a condition caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein, leading to increased susceptibility to mucus build-up, infection, and inflammation in the lungs and gastrointestinal tract. In June 2021, a new medication called elexacaftor/tezacaftor/ivacaftor (ETI; TRIKAFTA), made up of three drugs that restore CFTR function, was approved in Canada, which has potential to greatly improve the lives of Canadians living with CF. While it is evident that TRIKAFTA improves lung function, respiratory symptoms, and reduces the risk of exacerbation events (periods of worsening symptoms that can lead to hospitalization) in most patients, it is not clear how ETI therapy changes the inflammation and immune status of patients and what impact this has on their health.

The study project will involve the proteomic and transcriptomic analysis of blood biomarkers in relation to clinical outcomes including respiratory symptoms following the initiation of ETI. The student will enrol in the UBC Experimental Medicine MSc program and all experiments will be conducted at the Quon Lab in the UBC/St. Paul’s Hospital Centre for Heart Lung Innovation. 

For applicants, please send your cover letter, CV, and undergraduate transcripts to [email protected]

This posting is for the UBC Vancouver campus in British Columbia, Canada.

Please refer to reference number NC-56761 during correspondence about this position.

To express interest and initiate contact to the principal investigator applicants are encouraged to follow the instructions as provided in the position description or to submit the form on the Nature Careers website. Please note that applicants will have to complete an online application to the University of British Columbia and gain admission as a graduate student to the university. Applicants should review the graduate program profile to learn about admission requirements, application deadlines, program duration, tuition, or to read student and alumni stories. Please visit the researcher profile of the supervisor for this position to learn more about their research.

About UBC
The University of British Columbia is a global centre for research and teaching, consistently ranked among the top 20 public universities in the world. Since 1915, UBC’s entrepreneurial spirit has embraced innovation and challenged the status quo. UBC encourages its students, staff and faculty to challenge convention, lead discovery and explore new ways of learning. At UBC, bold thinking is given a place to develop into ideas that can change the world.

Research Master’s at UBC Vancouver
UBC is a public university with a comprehensive program offering – covering all major academic disciplines and degree levels, with both research- and course-based program options. More than 50,000 students attend UBC Vancouver. As a research master’s student at UBC Vancouver, you’ll be part of a diverse community of over 10,000 graduate students at an institution which is globally connected and attracts the highest-calibre research faculty. Work side by side with passionate scholars in modern facilities and with the support of numerous professional development workshops and services.

You are encouraged to review the awards and scholarship database to determine funding opportunities for your master’s degree. UBC invests significantly into its research programs and, combined with the International Tuition Award , offers most research-based Master programs at a comparable low tuition rate for domestic and international students alike.

About UBC’s Faculty of Medicine
Every day across British Columbia, trainees and researchers at the UBC Faculty of Medicine are turning skills into jobs, investments into discoveries, and discoveries into solutions that are transforming health for everyone.

The UBC Faculty of Medicine offers a diverse array of training opportunities including cutting-edge research experiences in the biosciences, globally recognized population health education, quality health professional training, as well as several certificate and online training options. The Faculty of Medicine is home to more than 1,700 graduate students housed in 23 graduate programs (14 of which offer doctoral research options). Year after year, research excellence in the Faculty of Medicine is supported by investment from funding sources here at home and around the globe, receiving approximately $1.6B in total research funding in the last five years.

About Vancouver
Vancouver is a dynamic, cosmopolitan and progressive city, consistently ranked as one of the top cities to live in the world. Canada’s third largest city has it all: sea, parks, mountains, beaches, and four seasons per year, including beautiful summers and mild, wet winters with snow in the mountains. It’s the perfect backdrop to your academic research.

View or Apply
To help us track our recruitment effort, please indicate in your cover//motivation letter where ( you saw this job posting.

Leave a Reply