General Manager, Canada

Astellas Pharma

Astellas Canada

At Astellas, we strive to become a cutting-edge, value-driven life science innovator. This means working at the forefront of healthcare change to turn innovative science into VALUE for patients.

What sets us apart is our focus on patients, our pioneering innovation, our collaborative culture, and the passion of our talented people.

Making a positive impact on patients’ lives is the purpose behind everything we do. At Astellas, we are relentless in our pursuit of scientific progress and in tackling unmet medical needs, demonstrated by our legacy in oncology, overactive bladder and transplant and our impressive pipeline in women’s health, blindness and regeneration, genetic regulation, immuno-oncology, mitochondria and targeted protein degradation.

About Us

We are a global pharmaceutical company headquartered in Japan, with a team of more than 14,000 managing operations in approximately 70 countries around the world. We are in the Top 30 global biopharma company based on global revenues and are predicted to be one of the Top 10 Cancer Drug Makers of 2024 by Fierce Pharma.

In Canada, we are growing to meet the exciting opportunities realized by our legacy brands and rich pipeline of innovative treatments.

We are looking for candidates who will thrive in our entrepreneurial and empowering environment where talent and leadership flourish. Do your values align with our Astellas Way – patient focus, ownership, results, openness, and integrity? Then we would love to hear from you.

From the first day in role, everyone at Astellas has a responsibility for creating a brighter future for patients around the world. We nurture exceptional relationships with our employees to allow them to thrive, foster innovation, and deliver exceptional business results. We work to create a culture where our people feel empowered to pursue brave ideas and ambitious outcomes, to have the confidence to be accountable for a higher standard of performance and embody a competitive and solutions-oriented mindset.

Our expertise, science and technology make us a pharma company. Our open and diverse culture is what makes us uniquely Astellas.

Astellas Pharma Canada (APCA) is currently searching for a General Manager, Canada reporting to the Head, Established Markets Commercial.


Overall responsibility for delivering the Affiliate business targets, executing business plans in line with the overall Regional & Corporate strategy and managing operational risk.

Essential Job Duties:

  • Create and execute the annual Affiliate business plan. Deliver the Affiliate P&L in line with agreed financial and scorecard objectives, directing allocation of commercial resources to maximize various in-market and new brand growth potential opportunities or risks.
  • Continuously review affiliate operating model, implementing changes to ensure it remains fit for purpose in strong collaboration with all functions.
  • Co-ordinate knowledge and understanding of the local market(s) to drive sustainable, profitable growth, enhancing operational efficiency, and advancing Astellas’ commercial goals.
  • Develop and manage long-term strategic partnerships with key individual, institutional stakeholders and trade associations, acting as an ambassador for the Astellas corporate brand, its reputation, products and product value; secure access to patients in line with global strategy; increase value for patients.
  • Consult and collaborate with matrix functional global & regional colleagues/teams to meet operational capability and performance needs across the affiliate.
  • Lead the Affiliate management team, ensuring alignment across the organisation and engaging all stakeholders. Develop the capabilities and competencies of the affiliate to deliver a culture of high performance; lead and manage coaching and development activities for commercial leaders to strengthen talent pipelines; building upon Canada’s leadership strong engagement and inclusive culture, keep on fostering sustainable employee engagement and empowerment, support talent acquisition & retention and strong performance management.
  • Actively contribute to Established Markets Leadership Team performance.
  • Collaborate on the delivery of all in-country compliance requirements, ensuring adherence to company and external codes of conduct, laws and regulations (including Healthcare, Legal, PV, Regulatory, Medical, HR, QA and environmental).
  • Legal and fiduciary board responsibilities for total Affiliate (including all employees) as statutory Director of local legal entity (including but not limited to H&S, GDPR, P&L/balance sheet) with corresponding civil and criminal liability (please also reference Group Company Governance Policy 287 and Directors and Officers Insurance Overview).


  • Priority Market
  • Employee Headcount Managed FY 2024: 54 / Total Affiliate: ~100
  • FY24 Budget: € 204 M
  • OpEx Y24 Budget: € 35M
  • Operating profit: FY24 Budget € 127M
  • Functions: Marketing, Sales, Market Access & Government Affairs, Operational Excellence, Communications, Patient Advocacy
  • Products (in-market / future brands): Xtandi, Xospata, Betmiga, Tacrolimus, Veoza, Vyloy, Izeray

Leadership Roles:

  • Reports to: Head of Established Markets Commercial
  • Member of the Established Markets Leadership Team (EMLT)
  • Divisional Risk and Resilience Committee (DRRC)
  • Leads local Management Team
  • Member of the Board of Directors

Key Relationships:


  • Established Commercial Markets Leadership team
  • Regional partners for Finance, Medical Affairs, Access, ComC, SBM, HR, Legal, Ethics& Compliance, Internal Audit


  • Professional and Regulatory bodies
  • Institutions / Trade Associations
  • Government bodies

Required Qualifications:

  • Knowledge usually gained through a university degree or at least 10 – 15 years of experience most typically in a commercial role, preferably GM already or a role closely aligned to supporting the commercial organization such as Finance, Medical, Market Access etc.
  • Proven ability, track record and experience to effectively lead and motivate teams.

Additional Information

Astellas Pharma Canada welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the hiring process.

Astellas Pharma Canada requires full Vaccination against COVID-19 as a condition of employment. Reasonable accommodation to this policy may be granted for a valid accommodation request under human rights legislation.

No telephone inquiries, in-person applications, or agencies please. While we appreciate all applications, only candidates under consideration will be contacted.

  • LI-CH1


Astellas is committed to equality of opportunity in all aspects of employment.

EOE including Disability/Protected Veterans

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