Clinical Data Architect & Engineer

Astellas Pharma

Astellas Canada – Medical Knowledge Architect & Engineer

At Astellas, we attempt to turn into a cutting-edge, value-driven life science innovator. This implies working on the forefront of healthcare change to show revolutionary science into VALUE for sufferers.

What units us aside is our give attention to sufferers, our pioneering innovation, our collaborative tradition, and the fervour of our proficient folks.

Making a optimistic influence on sufferers’ lives is the aim behind all the things we do. At Astellas, we’re relentless in our pursuit of scientific progress and in tackling unmet medical wants, demonstrated by our legacy in oncology, overactive bladder and transplant and our spectacular pipeline in girls’s well being, blindness and regeneration, genetic regulation, immuno-oncology, mitochondria and focused protein degradation.

About Us:

We’re a worldwide pharmaceutical firm headquartered in Japan, with a crew of greater than 14,000 managing operations in roughly 70 international locations all over the world. We’re within the High 30 international biopharma firm primarily based on international revenues and are predicted to be one of many High 10 Most cancers Drug Makers of 2024 by Fierce Pharma.

In Canada, we’re rising to satisfy the thrilling alternatives realized by our legacy manufacturers and wealthy pipeline of revolutionary remedies.

We’re on the lookout for candidates who will thrive in our entrepreneurial and empowering atmosphere the place expertise and management flourish. Do your values align with our Astellas Manner – affected person focus, possession, outcomes, openness and integrity? Then we’d love to listen to from you.

From the primary day in position, everybody at Astellas has a accountability for making a brighter future for sufferers all over the world. We nurture distinctive relationships with our workers to permit them to thrive, foster innovation, and ship distinctive enterprise outcomes. We work to create a tradition the place our folks really feel empowered to pursue courageous concepts and impressive outcomes, to have the boldness to be accountable for a better normal of efficiency and embody a aggressive and solutions-oriented mindset.

Our experience, science and know-how make us a pharma firm. Our open and various tradition is what makes us uniquely Astellas.

Astellas Pharma Canada (APCA) is at the moment looking for a Medical Knowledge Architect & Engineer reporting to Lead, Medical Knowledge Administration, FoundationX.


The Medical Knowledge Architect and Engineer position serves the aim of fostering innovation and operational effectivity by the facilitation of data-driven decision-making processes, expediting drug discovery initiatives, and bolstering regulatory compliance efforts. This position entails designing and implementing personalized knowledge structure options tailor-made to the complexities of life sciences analysis and improvement. It additionally contains supervising the combination and administration of varied knowledge sources, equivalent to medical trials knowledge, operational knowledge, genomic knowledge, and real-world proof.

Via shut collaboration with analysis scientists, statisticians, clinicians, regulatory specialists, and DigitalX professionals, this position establishes and upholds sturdy knowledge structure frameworks that align harmoniously with enterprise targets, regulatory mandates, and trade requirements. Experience in Knowledge Engineering, Knowledge Modeling, Enterprise Intelligence (BI) applied sciences, and adeptly managing governance processes is important for sustaining the integrity, safety, and accessibility of knowledge property. This position holds a strategic place in advancing the life sciences firm’s mission by utilizing knowledge to drive scientific progress, enhance affected person outcomes, and effectively and securely introduce ground-breaking therapies to the market.

Important Job Duties

  • Develop and keep complete knowledge structure methods tailor-made to the distinctive wants of Medical and Operational knowledge administration.
  • Design scalable, environment friendly, and safe databases, knowledge warehouses, and knowledge lakes to retailer and handle medical knowledge successfully.
  • Outline and implement knowledge fashions, schemas, and integration frameworks to make sure the integrity and accessibility of medical knowledge.
  • Lead all knowledge engineering duties and implement knowledge pipelines, ETL processes to ingest, remodel, and cargo medical knowledge from numerous sources into the information infrastructure.
  • Optimize knowledge workflows and efficiency by automation, parallel processing, and knowledge partitioning methods.
  • Collaborate with knowledge scientists and analysts to assist superior analytics, machine studying, and predictive modeling initiatives.
  • Combine disparate medical techniques, functions, and knowledge sources to allow interoperability and knowledge trade throughout the life sciences ecosystem.
  • Develop APIs, interfaces, and middleware options for seamless communication between medical software program techniques and databases.
  • Guarantee compatibility and compliance with trade requirements equivalent to HL7, FHIR, and others.
  • Implement safety controls, encryption mechanisms, and entry administration insurance policies to guard delicate knowledge from unauthorized entry, breaches, and cyber threats.
  • Monitor compliance with healthcare laws equivalent to HIPAA, GDPR, and different knowledge privateness legal guidelines, and implement measures to handle potential dangers and vulnerabilities.
  • Conduct efficiency tuning and optimization of databases, queries, and knowledge processing pipelines to reinforce effectivity, reliability, and scalability.
  • Monitor system well being, knowledge integrity, and efficiency metrics utilizing monitoring instruments and implement proactive measures to handle points and bottlenecks.
  • Doc knowledge structure designs, technical specs, and operational procedures to facilitate information switch and assist ongoing upkeep and enhancements.
  • Present steerage, coaching, and mentorship to crew members and stakeholders on finest practices in knowledge administration, structure, and engineering.
  • Work intently with cross-functional groups together with statisticians, statistical programmers, researchers, DigitalX members, and regulatory specialists to grasp necessities and priorities for medical knowledge administration and evaluation.
  • Talk successfully with stakeholders to make sure alignment of knowledge structure and engineering options with organizational objectives and targets.
  • Keep abreast of rising applied sciences, traits, and finest practices in medical knowledge administration, structure, and engineering.
  • Determine alternatives for course of enchancment, automation, and innovation to reinforce the effectivity and effectiveness of knowledge administration practices.


  • Experience in database design, knowledge modeling, and knowledge integration methods.
  • Proficiency in programming languages generally utilized in knowledge administration and evaluation, equivalent to SQL, SAS, Python, or R.
  • Experience in working with databases and knowledge warehousing applied sciences like SQL Server, Oracle, MySQL, AWS Redshift, Azure Synapse, Google BigQuery and so on.
  • Robust command in ETL and Knowledge Integration instruments like Talend, AWS Glue and DataBricks.
  • Expertise with Grasp Knowledge Administration (MDM) instruments like Veeva Community, Reltio and IBM Infosphere
  • Expertise with BI instruments like QlikSense, Tableau and PowerBI.
  • In-depth understanding of life sciences enterprise processes, adept at translating enterprise necessities into efficient technical options.
  • Revolutionary problem-solving skills for addressing advanced data-related challenges.
  • Expertise with Agile methodology and mindset.
  • Wonderful communication and interpersonal abilities, enabling efficient collaboration with cross-functional groups, enterprise stakeholders, and technical specialists.
  • Undertaking administration capabilities, making certain adherence to timelines for profitable resolution supply.
  • Demonstrated management abilities, together with guiding technical groups, providing mentorship, and influencing architectural selections.
  • Demonstrated dedication to staying present with the newest traits, applied sciences, and finest practices within the knowledge and analytics discipline.
  • Related certifications in cloud computing and knowledge analytics instruments/platforms are advantageous.


  • Bachelor of Science diploma in Laptop Science, Data Techniques, Knowledge Science, or a associated discipline.
  • 10+ years of related expertise working in in knowledge structure, engineering roles or associated roles inside a healthcare trade.

Most popular

  • 7+ years’ expertise in Life Sciences trade
  • Grasp of Science diploma in Laptop Science, Data Techniques, Knowledge Science, or a associated discipline.
  • Superior Analytics expertise

Extra Data

Astellas Pharma Canada welcomes and encourages functions from folks with disabilities. Lodging can be found on request for candidates participating in all elements of the hiring course of.

Astellas Pharma Canada requires full Vaccination in opposition to COVID-19 as a situation of employment. Cheap lodging to this coverage could also be granted for a sound lodging request below human rights laws.

No phone inquiries, in-person functions, or companies please. Whereas we admire all functions, solely candidates into account will probably be contacted.

  • LI-CH1

Class FoundationX

Astellas is dedicated to equality of alternative in all elements of employment.

EOE together with Incapacity/Protected Veterans

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